Anti-Mouse CD4 Antibody (Clone GK1.5) – Purified in vivo GOLD™ Functional Grade - 1.0 mg C1333-1.0 mg from Leinco Technologies, Inc.

Product Specs
ItemAnti-Mouse CD4 Antibody (Clone GK1.5) – Purified in vivo GOLD™ Functional Grade - 1.0 mg
CompanyLeinco Technologies, Inc.
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberC1333-1.0 mg
Quantity1.0 mg
ApplicationsB, Costim, CyTOF®, Depletion, FA, FC, IHC, in vivo, IP
Concentration≥ 5.0 mg/ml
Conjugate/TagUnconjugated
FormatThis monoclonal CD4 antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration
Purity≥95% monomer by analytical SEC, >95% by SDS Page
ReactivityMouse
TargetCD4
IsotypeIgG2b κ
CloneGK1.5
HostRat
ImmunogenMouse CTL clone V4
NCBI Full Gene NameCD4 antigen
NCBI Gene AliasesL3T4, Ly-4
ClonalityMonoclonal Antibody
Research AreaImmunology

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Leinco Technologies, Inc.

410 Axminister Drive

St. Louis, Missouri 63026

United States

Phone: (636) 230-9477
Orders or Customer Support: (800) 538-1145
Technical Support: (800) 538-1145

Email: leincoglobal@leinco.com

Company Profile

Website: www.leinco.com

(1) Autophagy prevents early proinflammatory responses and neutrophil recruitment during Mycobacterium tuberculosis infection without affecting pathogen burden in macrophagesPLoS biologyJune 1, 2023Kinsella RL, Kimmey JM, Smirnov A, Woodson R, Gaggioli MR, Chavez SM, Kreamalmeyer D, Stallings CL.finishing on 13 dpi. To deplete CD4+ T cells from mice, 250 μg of anti-mouse CD4 (Leinco Technologies, C1333) was administered by i.p. injection at 2 days prior to infection, 5 dpi, and 12 dpi. Control mice received

(2) A protein-based cGAS-STING nanoagonist enhances T cell-mediated anti-tumor immune responsesNature communicationsSeptember 28, 2022Wang X, Liu Y, Xue C, Hu Y, Zhao Y, Cai K, Li M, Luo Z.(Cell Signaling Technology, 4302, 1:1000). CD4 (Leinco Technologies, 53-6.7 C375), CD8 (Leinco Technologies, GK1.5 C1333). Fluorescent antibodies used in this study include: FITC-antiCD80 (Biolegend, 16-10A1, 50 μg), PE-antiCD86

(3) PD-1 Signaling Promotes Control of Chronic Viral Infection by Restricting Type-I-Interferon-Mediated Tissue DamageCell reportsNovember 26, 2019Raju S, Verbaro DJ, Egawa T.RRID:AB_315429 GL7-A647,Biolegend,CAT#144606; RRID:AB_2562185 Streptavidin-HRP,BD,CAT#554066 Anti-CD4 (for In vivo administration),Leinco,CAT#C1333; RRID:AB_2737452 Anti-CD8 (for In vivo administration),Leinco,CAT#C2442 Anti-IFNAR (for In vivo administration),Leinco,CAT#I-401;

(4) High-Dimensional Analysis Delineates Myeloid and Lymphoid Compartment Remodeling during Successful Immune-Checkpoint Cancer TherapyCellNovember 1, 2018Gubin MM, Esaulova E, Ward JP, Malkova ON, Runci D, Wong P, Noguchi T, Arthur CD, Meng W, Alspach E, et al.3/23),BioLegend,Cat# 124610 Anti-mouse CD8a (clone 53-6.7),Leinco,Cat# C375 Anti-mouse CD4 (clone GK1.5),Leinco,Cat# C1333 Anti-mouse CD62L (clone MEL-14 ),Leinco,Cat# C2118 Anti-mouse KLRG-1 (clone 2F1),Leinco,Cat# K155 Anti-mouse

(5) Contribution of NK cells to immunotherapy mediated by PD-1/PD-L1 blockadeThe Journal of clinical investigationOctober 1, 2018Hsu J, Hodgins JJ, Marathe M, Nicolai CJ, Bourgeois-Daigneault MC, Trevino TN, Azimi CS, Scheer AK, Randolph HE, Thompson TW, et al.

(6) Cellular and Humoral Immunity Protect against Vaginal Zika Virus Infection in MiceJournal of virologyApril 1, 2018Scott JM, Lebratti TJ, Richner JM, Jiang X, Fernandez E, Zhao H, Fremont DH, Diamond MS, Shin H.

(7) Temporally Distinct PD-L1 Expression by Tumor and Host Cells Contributes to Immune EscapeCancer immunology researchFebruary 1, 2017Noguchi T, Ward JP, Gubin MM, Arthur CD, Lee SH, Hundal J, Selby MJ, Graziano RF, Mardis ER, Korman AJ, et al.

(8) Characterization of self-T-cell response and antigenic determinants of U1A protein with bone marrow-derived dendritic cells in NZB x NZW F1 miceImmunologyJuly 1, 2001Suen JL, Wu CH, Chen YY, Wu WM, Chiang BL.

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Anti-Mouse CD4 Antibody (Clone GK1.5) – Purified in vivo GOLD™ Functional Grade - 1.0 mg from Leinco Technologies, Inc.

Leinco Technologies, Inc.

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Anti-Mouse CD4 Antibody (Clone GK1.5) – Purified in vivo GOLD™ Functional Grade - 1.0 mg from Leinco Technologies, Inc.

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